Optical spectroscopy for quantification of bulk breast tissue properties in adolescent girls: preliminary observations

Samantha N. Dick; Lothar Lilge

doi:10.1117/12.628512

12 October 2005 Optical spectroscopy for quantification of bulk breast tissue properties in adolescent girls: preliminary observations

Samantha N. Dick, Lothar Lilge

Author Affiliations +

Proceedings Volume 5970, Photonic Applications in Devices and Communication Systems; 59701F (2005) https://doi.org/10.1117/12.628512
Event: Photonics North, 2005, Toronto, Canada

Abstract

Optical technology holds considerable promise to improve early detection, diagnosis and risk assessment of breast cancer. Unlike current clinical risk assessment tools such as the Gail model, the most widely accepted risk assessment tool, optical risk assessment technology can be applied to the entire female population of all ages. This study is investigating the use of optical reflectance spectroscopy (ORS) as a possible breast tissue development monitoring tool for adolescent girls. Changes in breast development due to proliferation of mammary gland and the surrounding stroma are reflected in changes in breast tissue density and composition which can be interrogated optically. Modifications of development influenced by micronutrients and hormonal status from exposures (e.g. toxins), lifestyle and diet effects, may ultimately be tracked. Preliminary data suggests that ORS has the ability to detect differences in bulk tissue properties in the developing breast of adolescent girls when compared to developmental stages assessed by Tanner, regional variation within breast tissue structure and asymmetries between left and right breast size and shape. Spectral comparison of unilateral breast development permits adjusting the optode separation as function of developmental breast size to minimize optical sampling of pectoral muscle.

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Samantha N. Dick and Lothar Lilge "Optical spectroscopy for quantification of bulk breast tissue properties in adolescent girls: preliminary observations", Proc. SPIE 5970, Photonic Applications in Devices and Communication Systems, 59701F (12 October 2005); https://doi.org/10.1117/12.628512

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KEYWORDS

Breast

Tissue optics

Tissues

Breast cancer

Cancer

Optical spectroscopy

Absorbance

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