Normalized field autocorrelation function-based functional ultrasound

Bingxue Liu; Jianbo Tang; David Boas

doi:10.1117/12.2611492

4 April 2022 Normalized field autocorrelation function-based functional ultrasound

Bingxue Liu, Jianbo Tang, David Boas

Proceedings Volume PC12038, Medical Imaging 2022: Ultrasonic Imaging and Tomography; PC1203807 (2022) https://doi.org/10.1117/12.2611492
Event: SPIE Medical Imaging, 2022, San Diego, California, United States

Abstract

In this work, we proposed a novel normalized filed autocorrelation function (g1) –based functional ultrasound (fUS). We introduced a metrics derived from g1 function of ultrasound signals that is inversely proportional to blood flow and validated g1-fUS with in vivo experiments of whisker stimulation. Results show that g1-fUS is able to detect blood flow speed change in response to enhanced neural activity and is not affected by clutters compared to power Doppler based fUS, indicating that g1-fUS is a good candidate for whole brain functional imaging in small animals.

Conference Presentation

Citation Download Citation

Bingxue Liu, Jianbo Tang, and David Boas "Normalized field autocorrelation function-based functional ultrasound", Proc. SPIE PC12038, Medical Imaging 2022: Ultrasonic Imaging and Tomography, PC1203807 (4 April 2022); https://doi.org/10.1117/12.2611492

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