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7 March 2023 Multistate time-multiplexed system for functional time-domain diffuse correlation spectroscopy with SNSPDs
Marco Renna, Zachary Starkweather, Mitchell Robinson, Nisan Ozana, Alyssa Martin, Stefan Carp, Maria Angela Franceschini
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Proceedings Volume PC12376, Optical Tomography and Spectroscopy of Tissue XV; PC123760D (2023) https://doi.org/10.1117/12.2650215
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
We present a novel system based on a four-stage fiber delay network designed for multistate time-domain diffuse correlation spectroscopy, providing three output fibers per each delay state. The fiber delay network is coupled to a custom pulsed laser at 1064 nm and four SNSPDs, allowing to measure up to 12 independent source-detector pairs simultaneously. The system delivers 300ps optical pulses, 100 mW average optical power per fiber output, operates at 62.5 MHz and each cycle provides 4 laser pulses displaced of 4 ns. The instrument has been validated on healthy human subject during functional tasks, proving state-of-the-art performance.
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Marco Renna, Zachary Starkweather, Mitchell Robinson, Nisan Ozana, Alyssa Martin, Stefan Carp, and Maria Angela Franceschini "Multistate time-multiplexed system for functional time-domain diffuse correlation spectroscopy with SNSPDs", Proc. SPIE PC12376, Optical Tomography and Spectroscopy of Tissue XV, PC123760D (7 March 2023); https://doi.org/10.1117/12.2650215
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KEYWORDS
Spectroscopy
Brain
Blood circulation
Signal to noise ratio
Point spread functions
Pulsed laser operation
Single photon detectors
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