Ray-traced Monte Carlo simulation tool for computer-aided design of tissue fluorescence sensing system

Seung Yup Lee; Mary-Ann Mycek

doi:10.1117/12.2253334

14 March 2017 Ray-traced Monte Carlo simulation tool for computer-aided design of tissue fluorescence sensing system

Seung Yup Lee, Mary-Ann Mycek

Proceedings Volume 10056, Design and Quality for Biomedical Technologies X; 100560I (2017) https://doi.org/10.1117/12.2253334
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

In designing fluorescence spectroscopy and imaging systems for biological applications, a sample's own optical properties can significantly affect system performance. The independent use of Monte Carlo codes or optical design software often does not provide complete and accurate modeling of the fluorescence excitation and emission path through the optical components and turbid sample. We have developed a ray-traced Monte Carlo (RTMC) simulation method to track the complete light path by combining MC codes and ray-tracing software. Computational and experimental verification results demonstrate that RTMC has the potential to become a useful tool for designing tissue fluorescence sensing systems.

Citation Download Citation

Seung Yup Lee and Mary-Ann Mycek "Ray-traced Monte Carlo simulation tool for computer-aided design of tissue fluorescence sensing system", Proc. SPIE 10056, Design and Quality for Biomedical Technologies X, 100560I (14 March 2017); https://doi.org/10.1117/12.2253334

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