Cellular biophysical markers of hydroxyurea treatment in sickle cell disease

Peter T. C. So; Poorya Hosseini; Sabia Z. Abidi; E. Du; Dimitrios P. Papageorgiou; YongKeun Park; John Higgins; Gregory J. Kato; Subra Suresh; Ming Dao; Zahid Yaqoob

doi:10.1117/12.2273139

18 April 2017 Cellular biophysical markers of hydroxyurea treatment in sickle cell disease

Peter T. C. So, Poorya Hosseini, Sabia Z. Abidi, E. Du, Dimitrios P. Papageorgiou, YongKeun Park, John Higgins, Gregory J. Kato, Subra Suresh, Ming Dao, Zahid Yaqoob

Author Affiliations +

Proceedings Volume 10251, Biomedical Imaging and Sensing Conference; 1025103 (2017) https://doi.org/10.1117/12.2273139
Event: SPIE Technologies and Applications of Structured Light, 2017, Yokohama, Japan

Abstract

Using a common-path interferometric technique, we measure biomechanical and morphological properties of individual red blood cells in SCD patients as a function of cell density, and investigate the correlation of these biophysical properties with drug intake as well as other clinically measured parameters.

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Peter T. C. So, Poorya Hosseini, Sabia Z. Abidi, E. Du, Dimitrios P. Papageorgiou, YongKeun Park, John Higgins, Gregory J. Kato, Subra Suresh, Ming Dao, and Zahid Yaqoob "Cellular biophysical markers of hydroxyurea treatment in sickle cell disease", Proc. SPIE 10251, Biomedical Imaging and Sensing Conference, 1025103 (18 April 2017); https://doi.org/10.1117/12.2273139

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