Macroscopic assembly by optical control of zmol-level DNA hybridization

Takuya Iida; Yushi Nishimura; Mamoru Tamura; Keisuke Nishida; Syoji Ito; Shiho Tokonami

doi:10.1117/12.2275108

18 April 2017 Macroscopic assembly by optical control of zmol-level DNA hybridization

Takuya Iida, Yushi Nishimura, Mamoru Tamura, Keisuke Nishida, Syoji Ito, Shiho Tokonami

Proceedings Volume 10252, Optical Manipulation Conference; 102520J (2017) https://doi.org/10.1117/12.2275108
Event: SPIE Technologies and Applications of Structured Light, 2017, Yokohama, Japan

Abstract

Remote acceleration of a molecular recognition will open an avenue for the control of various biological functions. Here, we have developed a new principle for the rapid macroscopic assembly based on the light-induced molecular recognition via nanoparticles. Remarkably, as an application of this principle, we have demonstrated the submillimetre network formation triggered by light-induced hybridization of zmol-level DNA within a few minutes. This finding will be used for the rapid and highly sensitive genetic screening without fluorescent labeling.

Citation Download Citation

Takuya Iida, Yushi Nishimura, Mamoru Tamura, Keisuke Nishida, Syoji Ito, and Shiho Tokonami "Macroscopic assembly by optical control of zmol-level DNA hybridization", Proc. SPIE 10252, Optical Manipulation Conference, 102520J (18 April 2017); https://doi.org/10.1117/12.2275108

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