The use of optical coherence tomography to analyze the efficacy of skin care products

Sarosh Irani; Zahra Turani; Audrey Fotouhi; Steven Daveluy; Darius Mehregan; Wei Chen; Juri Gelovani; Mohammadreza Nasiriavanaki

doi:10.1117/12.2291404

21 February 2018 The use of optical coherence tomography to analyze the efficacy of skin care products

Sarosh Irani, Zahra Turani, Audrey Fotouhi, Steven Daveluy, Darius Mehregan, Wei Chen, Juri Gelovani, Mohammadreza Nasiriavanaki

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Proceedings Volume 10467, Photonics in Dermatology and Plastic Surgery 2018; 1046715 (2018) https://doi.org/10.1117/12.2291404
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

In this study, we assess the applicability of optical coherence tomography (OCT) for non-invasive imaging of skin morphology for the assessment of efficacy of cosmetic skin wrinkle-reduction products in humans. Evaluation of skin care products for reduction of facial wrinkles is largely limited to photographic (non-quantitative) comparison of skin surface texture before and after either single or prolonged application of skin care product. OCT could be a technique for monitoring changes in cross-sectional skin morphology. An optical attenuation coefficient analysis is also carried out to quantitatively study the changes in different layers of the skin.

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Sarosh Irani, Zahra Turani, Audrey Fotouhi, Steven Daveluy, Darius Mehregan, Wei Chen, Juri Gelovani, and Mohammadreza Nasiriavanaki "The use of optical coherence tomography to analyze the efficacy of skin care products", Proc. SPIE 10467, Photonics in Dermatology and Plastic Surgery 2018, 1046715 (21 February 2018); https://doi.org/10.1117/12.2291404

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KEYWORDS

Skin

Optical coherence tomography

Surface roughness

Analytical research

Tissue optics

Image resolution

Statistical analysis

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