Real-time in vivo imaging of human lymphatic system using an LED-based photoacoustic/ultrasound imaging system

Mithun Kuniyil Ajith Singh; Toshitaka Agano; Naoto Sato; Yusuke Shigeta; Tetsuji Uemura

doi:10.1117/12.2290871

19 February 2018 Real-time in vivo imaging of human lymphatic system using an LED-based photoacoustic/ultrasound imaging system

Mithun Kuniyil Ajith Singh, Toshitaka Agano, Naoto Sato, Yusuke Shigeta, Tetsuji Uemura

Author Affiliations +

Proceedings Volume 10494, Photons Plus Ultrasound: Imaging and Sensing 2018; 1049404 (2018) https://doi.org/10.1117/12.2290871
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

Non-invasive in vivo imaging of lymphatic system is of paramount importance for analyzing the functions of lymphatic vessels, and for investigating their contribution to metastasis. Recently, we introduced a multi-wavelength real-time LED-based photoacoustic/ultrasound system (AcousticX). In this work, for the first time, we demonstrate that AcousticX is capable of real-time imaging of human lymphatic system. Results demonstrate the capability of this system to image vascular and lymphatic vessels simultaneously. This could potentially provide detailed information regarding the interconnected roles of lymphatic and vascular systems in various diseases, therefore fostering the growth of therapeutic interventions.

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Mithun Kuniyil Ajith Singh, Toshitaka Agano, Naoto Sato, Yusuke Shigeta, and Tetsuji Uemura "Real-time in vivo imaging of human lymphatic system using an LED-based photoacoustic/ultrasound imaging system", Proc. SPIE 10494, Photons Plus Ultrasound: Imaging and Sensing 2018, 1049404 (19 February 2018); https://doi.org/10.1117/12.2290871

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