Transurethral illumination probe design for deep photoacoustic imaging of prostate

Min Ai; Tim Salcudean; Robert Rohling; Purang Abolmaesumi; Shuo Tang

doi:10.1117/12.2291164

19 February 2018 Transurethral illumination probe design for deep photoacoustic imaging of prostate

Min Ai, Tim Salcudean, Robert Rohling, Purang Abolmaesumi, Shuo Tang

Proceedings Volume 10494, Photons Plus Ultrasound: Imaging and Sensing 2018; 104940C (2018) https://doi.org/10.1117/12.2291164
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

Photoacoustic (PA) imaging with internal light illumination through optical fiber could enable imaging of internal organs at deep penetration. We have developed a transurethral probe with a multimode fiber inserted in a rigid cystoscope sheath for illuminating the prostate. At the distal end, the fiber tip is processed to diffuse light circumferentially over 2 cm length. A parabolic cylinder mirror then reflects the light to form a rectangular-shaped parallel beam which has at least 1 cm² at the probe surface. The relatively large rectangular beam size can reduce the laser fluence rate on the urethral wall and thus reduce the potential of tissue damage. A 3 cm optical penetration in chicken tissue is achieved at a fluence rate around 7 mJ/cm² . For further validation, a prostate phantom was built with similar optical properties of the human prostate. A 1.5 cm penetration depth is achieved in the prostate mimicking phantom at 10 mJ/cm² fluence rate. PA imaging of prostate can potentially be carried out in the future by combining a transrectal ultrasound transducer and the transurethral illumination.

Conference Presentation

Citation Download Citation

Min Ai, Tim Salcudean, Robert Rohling, Purang Abolmaesumi, and Shuo Tang "Transurethral illumination probe design for deep photoacoustic imaging of prostate", Proc. SPIE 10494, Photons Plus Ultrasound: Imaging and Sensing 2018, 104940C (19 February 2018); https://doi.org/10.1117/12.2291164

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available