Conventional X-ray computed tomography (CT) only reconstructs the attenuation map. X-ray coherent scattering computed tomography (CSCT) probes the angular-dependent scattering profiles of the three-dimensional (3D) object, achieving a high structural specificity among materials with similar electron density. However, due to the low level of interaction of coherent scattering and the 3D scattering profiles of crystalline materials, the real-life anomaly detection using coherent scattering signature posed challenges in acquisition speed, algorithm efficiency, reconstruction quality, and detection accuracy. In this invited talk, we will discuss the efforts in accelerating the image acquisition speed while maintaining object-specific information from the Optical Imaging System Lab at the University of Central Florida. Specifically, the talk will be focus on maximize the system detection efficiency and improve the classification/reconstruction performance for low photon detection level to meet the need of practical detection.
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