Presentation + Paper
1 March 2019 Long-term photoacoustic brain imaging in a freely moving rat
Author Affiliations +
Proceedings Volume 10865, Neural Imaging and Sensing 2019; 108650W (2019) https://doi.org/10.1117/12.2507790
Event: SPIE BiOS, 2019, San Francisco, California, United States
Abstract
Photoacoustic microscopy (PAM) is an emerging technique extensively used to study brain activities. However, limited by the size and performance of optical/acoustic scanners, existing ORPAMs are still bulky, heavy, and suffer from low imaging quality/speed. Here, we develop a wearable ORPAM probe featuring small, light, fast, and cellular imaging capability. To evaluate the probe, we monitored the cerebral vascular network within two hours and demonstrated that the microscope was stable enough to study long-term brain hemodynamics in a freely moving rat.
Conference Presentation
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Qian Chen and Lei Xi "Long-term photoacoustic brain imaging in a freely moving rat", Proc. SPIE 10865, Neural Imaging and Sensing 2019, 108650W (1 March 2019); https://doi.org/10.1117/12.2507790
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KEYWORDS
Photoacoustic spectroscopy

Hemodynamics

Brain

Brain imaging

Signal detection

Image resolution

Microscopes

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