Pilot study for detection of cutaneous melanoma boundary using photoacoustic imaging

Jeesu Kim; Byullee Park; Yeong Ho Kim; Hyun-Min Seo; Chul Hwan Bang; Gyeong Sin Park; Young Min Park; Jong Won Rhie; Ji Hyun Lee; Chulhong Kim

doi:10.1117/12.2506608

27 February 2019 Pilot study for detection of cutaneous melanoma boundary using photoacoustic imaging

Jeesu Kim, Byullee Park, Yeong Ho Kim, Hyun-Min Seo, Chul Hwan Bang, Gyeong Sin Park, Young Min Park, Jong Won Rhie, Ji Hyun Lee, Chulhong Kim

Author Affiliations +

Proceedings Volume 10878, Photons Plus Ultrasound: Imaging and Sensing 2019; 108785L (2019) https://doi.org/10.1117/12.2506608
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

The standard method to treat cutaneous melanoma, which is the most prevalent skin cancer, is surgical excision of visible boundary with an additional margin. The margin is typically decided by surgeons’ experience based on the color of the lesion. It is very important to determine appropriate excision area because the operation will continue until a histological evaluation is made the there is no cancerous cells in the excised margin. Here, we demonstrate the results from our initial pilot study for detection of melanoma boundary using photoacoustic (PA) imaging. We recruited a patient who had a cutaneous melanoma lesion on the left heel. We excised the lesion with surgical operation by adding ~1 cm margin to the visible boundary, and then immediately acquired multispectral PA images of the lesion. By scanning a linear array transducer using a motorized stage, we acquired volumetric PA images of the lesion. From the multispectral analysis of PA signals, we could tell cutaneous melanoma from surrounding normal tissue and marking pen. Although much more studies are required for clinical evaluation, the initial results demonstrate that the PA imaging can provide additional information to surgeons for better selection of excision area of cutaneous melanoma.

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Jeesu Kim, Byullee Park, Yeong Ho Kim, Hyun-Min Seo, Chul Hwan Bang, Gyeong Sin Park, Young Min Park, Jong Won Rhie, Ji Hyun Lee, and Chulhong Kim "Pilot study for detection of cutaneous melanoma boundary using photoacoustic imaging", Proc. SPIE 10878, Photons Plus Ultrasound: Imaging and Sensing 2019, 108785L (27 February 2019); https://doi.org/10.1117/12.2506608

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