Light distribution monitoring using an IR navigation system for pleural PDT (Conference Presentation)

Timothy C. Zhu; Michele M. Kim; Yihong Ong; Andreea Dimofte; Sunil Singhal; Keith A. Cengel

doi:10.1117/12.2527789

20 August 2019 Light distribution monitoring using an IR navigation system for pleural PDT (Conference Presentation)

Timothy C. Zhu, Michele M. Kim, Yihong Ong, Andreea Dimofte, Sunil Singhal, Keith A. Cengel

Author Affiliations +

Proceedings Volume 11070, 17th International Photodynamic Association World Congress; 110705N (2019) https://doi.org/10.1117/12.2527789
Event: 17th International Photodynamic Association World Congress, 2019, Cambridge, Massachusetts, United States

Abstract

Uniform delivery of light fluence is an important goal for photodynamic therapy. We present summary results for an infrared (IR) navigation system to deliver light dose uniformly during intracavitory PDT by tracking the movement of the light source and providing real-time feedback on the light fluence rate on the entire cavity surface area. In the current intrapleural PDT protocol, 8 detectors placed in selected locations in the pleural cavity monitor the light doses. To improve the delivery of light dose uniformity, an IR camera system is used to track the motion of the light source as well as the surface contour of the pleural cavity. A MATLAB-based GUI program is developed to display the light dose in real-time during PDT to guide the PDT treatment delivery to improve the uniformity of the light dose. We have developed an improved model for direct light calculation that accounts for the anisotropy of the light from the light sources. A comprehensive analysis of the distribution of light fluence during HPPH and Photofrin PDT is presented in clinical cases and the improvements between the two protocol are discussed.

Conference Presentation

Citation Download Citation

Timothy C. Zhu, Michele M. Kim, Yihong Ong, Andreea Dimofte, Sunil Singhal, and Keith A. Cengel "Light distribution monitoring using an IR navigation system for pleural PDT (Conference Presentation)", Proc. SPIE 11070, 17th International Photodynamic Association World Congress, 110705N (20 August 2019); https://doi.org/10.1117/12.2527789

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE