In vivo time domain speckle contrast optical spectroscopy

M. Pagliazzi; E. E. Vidal-Rosas; S. Konugolu Venkata Sekar; L. Di Sieno; L. Colombo; D. Contini; A. Torricelli; A. Pifferi; A. Dalla Mora; J. P. Culver; T. Durduran

doi:10.1117/12.2526651

11 July 2019 In vivo time domain speckle contrast optical spectroscopy

M. Pagliazzi, E. E. Vidal-Rosas, S. Konugolu Venkata Sekar, L. Di Sieno, L. Colombo, D. Contini, A. Torricelli, A. Pifferi, A. Dalla Mora, J. P. Culver, T. Durduran

Author Affiliations +

Proceedings Volume 11074, Diffuse Optical Spectroscopy and Imaging VII; 1107411 (2019) https://doi.org/10.1117/12.2526651
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

We propose a time domain speckle contrast optical spectroscopy (SCOS) system that makes use of a gated detector and pulsed light source to measure the blood flow variations at very short, quasi-null (<3mm) source-detector separation. We present the results of a human arm cuff occlusion and a comparison with standard SCOS, highlighting that we can probe deeper into tissue, reduce probe footprint, make efficient use of the signal and decrease cost.3

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M. Pagliazzi, E. E. Vidal-Rosas, S. Konugolu Venkata Sekar, L. Di Sieno, L. Colombo, D. Contini, A. Torricelli, A. Pifferi, A. Dalla Mora, J. P. Culver, and T. Durduran "In vivo time domain speckle contrast optical spectroscopy", Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 1107411 (11 July 2019); https://doi.org/10.1117/12.2526651

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KEYWORDS

Speckle

Photons

Sensors

Optical spectroscopy

Blood circulation

Electronics

Tissue optics

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