Scope of using ballistic photons for applications in biological tissue

Erick Ipus; Beethoven Bravo-Medina; Marija Strojnik

doi:10.1117/12.2525101

9 September 2019 Scope of using ballistic photons for applications in biological tissue

Erick Ipus, Beethoven Bravo-Medina, Marija Strojnik

Proceedings Volume 11128, Infrared Remote Sensing and Instrumentation XXVII; 111280W (2019) https://doi.org/10.1117/12.2525101
Event: SPIE Optical Engineering + Applications, 2019, San Diego, California, United States

Abstract

The use of transillumination to diagnose and consequently treat illnesses has been widely accepted for a long time. However, some kinds of radiation are harmful to the human body, as is the case for x-rays. In this work, we propose using infrared radiation as an illumination source, ballistic photons to transilluminate thin samples and separate scattered radiation from the pass-through radiation for potential future applications in biological research. Infrared radiation is less energetic and harmful than x-rays. Ballistic photons can supply information about the propagation medium, which in turn may allow us to detect inclusions below 9 mm in size (the limit of x-ray radiation) in the medium. In the initial research, we model biological tissue with controlled thickness of samples of pig tissue that has been processed for human consumption, i.e., slices of ham, to study the effects of ballistic photons and to assess the scope of this technique. The combination of an alternative illumination source and a simulated tissue allows us to assess calibration and the diagnostic technique. To detect irradiance, we implemented a Mach-Zehnder interferometer with a 633 nm wavelength He-Ne laser (NIR). As a detector, we used a Sony XCD-SX910 camera. We measure maximum and minimum irradiances generated by ballistic radiation as a function of the thickness of the tissue model and the measured point. The results of these measurements and their comparison are presented.

Citation Download Citation

Erick Ipus, Beethoven Bravo-Medina, and Marija Strojnik "Scope of using ballistic photons for applications in biological tissue", Proc. SPIE 11128, Infrared Remote Sensing and Instrumentation XXVII, 111280W (9 September 2019); https://doi.org/10.1117/12.2525101

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KEYWORDS

Photons

Glasses

Absorption

Tissue optics

Tissues

Diagnostics

Interferometry

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