Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging (Conference Presentation)

Yan Li; Zhikai Zhu; Jason J. Chen; Joseph C. Jing; Zhongping Chen

doi:10.1117/12.2542964

9 March 2020 Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging (Conference Presentation)

Yan Li, Zhikai Zhu, Jason J. Chen, Joseph C. Jing, Zhongping Chen

Author Affiliations +

Proceedings Volume 11232, Multimodal Biomedical Imaging XV; 112320F (2020) https://doi.org/10.1117/12.2542964
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Endoscopic optical coherence tomography (OCT) and near-infrared (NIR) fluorescence imaging system was developed for characterization of colorectal cancer (CRC). NIR fluorescence is able to highlight the cancer-suspected area based on significant change of tumor vascular density and morphology. Co-registered OCT images has the capability of visualizing subsurface tissue layer architecture, so the suspected regions can be further investigated by the altered light scattering resulted from the morphological abnormality. The imaging result from in vivo rat experiment has demonstrated the enhanced capability of identification and classification of CRC compared to using any of these technologies alone, thus has the potential to provide a new clinical tool to advance gastroenterology practice.

Conference Presentation

Citation Download Citation

Yan Li, Zhikai Zhu, Jason J. Chen, Joseph C. Jing, and Zhongping Chen "Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging (Conference Presentation)", Proc. SPIE 11232, Multimodal Biomedical Imaging XV, 112320F (9 March 2020); https://doi.org/10.1117/12.2542964

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available