Overlapping volumes, acousto-optic modulated diffuse correlation spectroscopy for increased depth sensitivity (Conference Presentation)

Mitchell B. Robinson; Stefan A. Carp; Sava Sakadzic; Adriano Peruch; Davide Tamborini; Maria Angela Franceschini

doi:10.1117/12.2546630

20 April 2020 Overlapping volumes, acousto-optic modulated diffuse correlation spectroscopy for increased depth sensitivity (Conference Presentation)

Mitchell B. Robinson, Stefan A. Carp, Sava Sakadzic, Adriano Peruch, Davide Tamborini, Maria Angela Franceschini

Author Affiliations +

Proceedings Volume 11240, Photons Plus Ultrasound: Imaging and Sensing 2020; 112402T (2020) https://doi.org/10.1117/12.2546630
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Diffuse correlation spectroscopy (DCS) is an established diffuse optical technique that uses the analysis of temporal speckle intensity fluctuations to measure blood flow in tissue. As a non-invasive technique, DCS has been used to monitor patient cerebral blood flow at the bedside. Though an effective measurement tool, extra-cerebral contamination of the DCS signal limits the sensitivity to changes in brain blood flow. In order to overcome this depth sensitivity challenge, we present a method, overlapping volumes, acousto-optic modulated DCS (AOM-DCS), to improve sensitivity to deeper tissue structures.

Conference Presentation

Citation Download Citation

Mitchell B. Robinson, Stefan A. Carp, Sava Sakadzic, Adriano Peruch, Davide Tamborini, and Maria Angela Franceschini "Overlapping volumes, acousto-optic modulated diffuse correlation spectroscopy for increased depth sensitivity (Conference Presentation)", Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112402T (20 April 2020); https://doi.org/10.1117/12.2546630

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