Design and implementation of low-cost linear laser scanning system for photoacoustic imaging

Hassan S. Salehi; John D. Schad

doi:10.1117/12.2547221

17 February 2020 Design and implementation of low-cost linear laser scanning system for photoacoustic imaging

Hassan S. Salehi, John D. Schad

Proceedings Volume 11240, Photons Plus Ultrasound: Imaging and Sensing 2020; 112403I (2020) https://doi.org/10.1117/12.2547221
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Photoacoustic imaging is a hybrid imaging technique with broad preclinical and clinical applications. Most of the optical-resolution photoacoustic microscopy (PAM) configurations are based on 3D scanning motor to scan the transducer together with the imaged sample or utilizing galvanometer scanning mirrors. In this paper, a novel low-cost linear laser scanning (LLS) system for photoacoustic microscopy is presented. The linear laser scanning system performs the two-dimensional scanning of the beam across a focusing lens. The prototype built for LLS system features a precision machined aluminum base with mounting platforms for optical components to insure proper alignment through the imaging process. The LLS relies on two stepper motors (1.8-degree, 200 steps per revolution) separately actuated, to move two 45-degree mirror mounts set onto high precision linear slides (44.5 mm of travel) which allow the laser beam to be moved across a tissue sample in a 2D axis. The threaded rod which is used to connect the linear slides and mirror assemblies has a travel distance per turn of 1/20.8” meaning for every inch of travel the rod must turn 20.8 times. The mechanical resolution of the system was estimated to be 6 μm. In this system, a pulsed laser diode with a wavelength of peak radiant intensity of 905 nm and output peak power of 220 W with 50 ns pulse width and repetition rate of 10 kHz was utilized as a light source.

Citation Download Citation

Hassan S. Salehi and John D. Schad "Design and implementation of low-cost linear laser scanning system for photoacoustic imaging", Proc. SPIE 11240, Photons Plus Ultrasound: Imaging and Sensing 2020, 112403I (17 February 2020); https://doi.org/10.1117/12.2547221

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KEYWORDS

Laser systems engineering

Laser scanners

Imaging systems

Semiconductor lasers

Photoacoustic imaging

Laser tissue interaction

Photoacoustic microscopy

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