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We recently proposed an alternative elasticity measurement technique based on elastic wave propagation within a single cell. Waves are capture using an ultrafast camera and a microscope. This technique is based on the local measurement of the speed vs of a shear wave, a type of elastic wave. By assuming an infinite and homogeneous elastic medium with respect to the wavelength, the shear modulus μ (elasticity) is estimated. These latter assumptions are discussed through experiments conducted in controlled elastic solids. The conclusion is that wave guide effects as well as viscosity are crucial for quantitative mapping of elasticity.
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Stefan Catheline, Gabrielle Laloy-Borgna, Ali Zorgani, Bruno Giammarinaro, Pol Grasland-Mongrain, "Complex elastic wave propagation in micro-elastography (Conference Presentation)," Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 1124208 (9 March 2020); https://doi.org/10.1117/12.2551486