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9 March 2020 Simultaneously imaging and quantifying in vivo mechanical properties of crystalline lens and cornea using optical coherence elastography with acoustic radiation force excitation (Conference Presentation)
Yan Li, Jiang Zhu, Jason J. Chen, Qifa Zhou, Zhongping Chen
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Proceedings Volume 11242, Optical Elastography and Tissue Biomechanics VII; 112420Z (2020) https://doi.org/10.1117/12.2545366
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
The changes in biomechanical properties of lens and cornea are closely correlated with presbyopia and cataract. We developed an optical coherence elastography system utilizing acoustic radiation force excitation to simultaneously assess the elasticities of the crystalline lens and the cornea in vivo. A swept light source was integrated into the system to provide an enhanced imaging range that covers both the lens and the cornea. Additionally, the oblique imaging approach combined with orthogonal excitation also improved the image quality. Simultaneous elasticity measurements of lens and cornea were performed in anesthetized rabbits to demonstrate the capability of ARF-OCE to characterize in vivo elasticity in the anterior eye.
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Yan Li, Jiang Zhu, Jason J. Chen, Qifa Zhou, and Zhongping Chen "Simultaneously imaging and quantifying in vivo mechanical properties of crystalline lens and cornea using optical coherence elastography with acoustic radiation force excitation (Conference Presentation)", Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 112420Z (9 March 2020); https://doi.org/10.1117/12.2545366
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KEYWORDS
In vivo imaging
Cornea
Crystals
Acoustics
Coherence (optics)
Elastography
Eye
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