Determination of the diffusion coefficient of rivanol in dentin of a human tooth in vitro

A. A. Selifonov; V. V. Tuchin

doi:10.1117/12.2556085

8 May 2020 Determination of the diffusion coefficient of rivanol in dentin of a human tooth in vitro

A. A. Selifonov, V. V. Tuchin

Proceedings Volume 11359, Biomedical Spectroscopy, Microscopy, and Imaging; 113591S (2020) https://doi.org/10.1117/12.2556085
Event: SPIE Photonics Europe, 2020, Online Only

Abstract

In the work, the effective diffusion coefficient of an aqueous solution of the pharmaceutical preparation rivanol in slices of human tooth dentin was experimentally determined using the method of reflection spectroscopy. Within the framework of the free diffusion model, in calculations using the second Fick law and the Bouguer-Lambert-Beer law for the optical model, the effective diffusion coefficient of the photosensitizer was calculated, which turned out to be equal on average (2.27 ± 0.32)·10^–6 cm²/s (n = 10).

Citation Download Citation

A. A. Selifonov and V. V. Tuchin "Determination of the diffusion coefficient of rivanol in dentin of a human tooth in vitro", Proc. SPIE 11359, Biomedical Spectroscopy, Microscopy, and Imaging, 113591S (8 May 2020); https://doi.org/10.1117/12.2556085

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