Field-effect electro-plasmonics: a quantum leap in neurotechnologies

Ahsan Habib; Xiangchao Zhu; Uryan I. Can; Maverick McLanahan; Pinar Zorlutuna; Ahmet Ali Yanik

doi:10.1117/12.2569154

4 September 2020 Field-effect electro-plasmonics: a quantum leap in neurotechnologies

Ahsan Habib, Xiangchao Zhu, Uryan I. Can, Maverick McLanahan, Pinar Zorlutuna, Ahmet Ali Yanik

Proceedings Volume 11461, Active Photonic Platforms XII; 1146129 (2020) https://doi.org/10.1117/12.2569154
Event: SPIE Nanoscience + Engineering, 2020, Online Only

Abstract

Harnessing the unprecedented spatiotemporal resolution capability of light to detect electrophysiological signals has been the goal of neuroscientists for nearly 50 years. Yet, progress towards that goal remains elusive due to lack of electro-optic translators that can efficiently convert bioelectronic signals to high photon-count optical signals. Here, we introduce an ultrasensitive and extremely bright field-effect active plasmonic nanoantenna translating tiny electric field oscillations to large optical signals in the far-field. Our electrochromically loaded plasmonic nanoprobes overcome the limitation of state-of-art neuroelectrode technologies and enable massively multiplexed measurement of nanoscale electric-field modulations. In our experiments, we demonstrated 500 million parallel, ultrasensitive and subcellular resolution recordings of cell firing behavior, reflecting a technical capability that is well beyond the theoretical limits of the state-of-art neurotechnologies.

Citation Download Citation

Ahsan Habib, Xiangchao Zhu, Uryan I. Can, Maverick McLanahan, Pinar Zorlutuna, and Ahmet Ali Yanik "Field-effect electro-plasmonics: a quantum leap in neurotechnologies", Proc. SPIE 11461, Active Photonic Platforms XII, 1146129 (4 September 2020); https://doi.org/10.1117/12.2569154

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available