Presentation
27 August 2020 Advanced neural interfaces and drug delivery
Author Affiliations +
Abstract
Here we report recent advances in precise engineering to incorporate advanced electrophoretic drug delivery system into implantable devices for treating neurological disorders including both depth probes and cortical arrays with recording capabilities. The efficacy of the platform is demonstrated by stopping epileptic seizures in vivo. This is the first in vivo demonstration of an electrophoretic implant treating a neurological disorder and offers a glimpse of what can be achieved by tailored engineering of electrophoretic devices. We anticipate this work to be the starting point for new stimulation, recording and drug delivery paradigms in chronic neural implantation.
Conference Presentation
© (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Christopher Proctor "Advanced neural interfaces and drug delivery", Proc. SPIE 11475, Organic and Hybrid Sensors and Bioelectronics XIII, 1147505 (27 August 2020); https://doi.org/10.1117/12.2568008
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KEYWORDS
Ions

Neurological disorders

Microfluidics

Neurotransmitters

Tissues

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