Differential diagnosis of adenocarcinoma and squamous cell carcinoma of the cervix by spectropolarimetry

Olexander Peresunko; Christina Felde; Sergey Yermolenko

doi:10.1117/12.2568399

21 August 2020 Differential diagnosis of adenocarcinoma and squamous cell carcinoma of the cervix by spectropolarimetry

Olexander Peresunko, Christina Felde, Sergey Yermolenko

Proceedings Volume 11510, Applications of Digital Image Processing XLIII; 115102L (2020) https://doi.org/10.1117/12.2568399
Event: SPIE Optical Engineering + Applications, 2020, Online Only

Conference Poster

Abstract

The aim of this work is to improve the diagnosis of cervical cancer by introducing laser polarimetry and spectropolarization methods of investigation. We have proposed a novel approach for the differentiation of squamous cell carcinoma and cervical adenocarcinoma using laser optics. Obtained by the method of laser polarimetry by Stokes parameter S4 of native smear with adenocarcinoma of the cervix and squamous cell carcinoma, as well as scraping of the mud canal with endometrial adenocarcinoma and flat cell cancer allows to reliably differentiate the norm from cancer in the native smear and adenocarcinoma from the flat cell cancer in the smear-imprint. The method of spectropolarimetry allows reliably accurately distinguishing the normal epithelium of the cervix from cancer of the cervix, and the parameters of linear dichroism during the spectropolarization study, reliably (р=0,001) differentiate between normal, adenocarcinoma and flat cell cancer of the cervix.

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Olexander Peresunko, Christina Felde, and Sergey Yermolenko "Differential diagnosis of adenocarcinoma and squamous cell carcinoma of the cervix by spectropolarimetry", Proc. SPIE 11510, Applications of Digital Image Processing XLIII, 115102L (21 August 2020); https://doi.org/10.1117/12.2568399

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