Dual energy chest x-ray for improved COVID-19 detection using a dual-layer flat-panel detector: simulation and phantom studies

Linxi Shi; N. Robert Bennett; Minghui Lu; Mingshan Sun; Jin Zhang; Josh Star-Lack; Emily B. Tsai; H. Henry Guo; Adam S. Wang

doi:10.1117/12.2581317

15 February 2021 Dual energy chest x-ray for improved COVID-19 detection using a dual-layer flat-panel detector: simulation and phantom studies

Linxi Shi, N. Robert Bennett, Minghui Lu, Mingshan Sun, Jin Zhang, Josh Star-Lack, Emily B. Tsai, H. Henry Guo, Adam S. Wang

Author Affiliations +

Proceedings Volume 11595, Medical Imaging 2021: Physics of Medical Imaging; 1159528 (2021) https://doi.org/10.1117/12.2581317
Event: SPIE Medical Imaging, 2021, Online Only

Abstract

Chest radiography (CXR) plays an important role in triage, management, and monitoring of patients with COVID-19. In this work, we use a dual-layer (DL) flat-panel detector to perform artifact-free single-exposure DE CXR for COVID-19 detection. A simulation study was performed to generate DE CXRs from CT volumes of 13 patients diagnosed with COVID-19, which were compared with simulated conventional CXR by two chest radiologists. A phantom study was also conducted using an anthropomorphic chest phantom with synthetic opacifications. Improved visualization of opacities was observed for DE CXRs in both studies, indicating that the proposed DL detector could be a powerful new tool for COVID-19 diagnosis and patient management.

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Linxi Shi, N. Robert Bennett, Minghui Lu, Mingshan Sun, Jin Zhang, Josh Star-Lack, Emily B. Tsai, H. Henry Guo, and Adam S. Wang "Dual energy chest x-ray for improved COVID-19 detection using a dual-layer flat-panel detector: simulation and phantom studies", Proc. SPIE 11595, Medical Imaging 2021: Physics of Medical Imaging, 1159528 (15 February 2021); https://doi.org/10.1117/12.2581317

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