An optical, endoscopic brush for high-yield diagnostics in esophageal cancer

S. Anandasabapathy; X. Zhang; M. Anastasio; R. Richards-Kortum; E. Petrova

doi:10.1117/12.2583301

8 March 2021 An optical, endoscopic brush for high-yield diagnostics in esophageal cancer

S. Anandasabapathy, X. Zhang, M. Anastasio, R. Richards-Kortum, E. Petrova

Proceedings Volume 11620, Endoscopic Microscopy XVI; 116200B (2021) https://doi.org/10.1117/12.2583301
Event: SPIE BiOS, 2021, Online Only

Abstract

Barrett’s esophagus is the main pre-cancer risk factor for the development of esophageal adenocarcinoma. Over the last decades, the incidence rate of esophageal adenocarcinoma increases exponentially in the Western World. Endoscopic screening and minimally-invasive treatment of Barrett’s esophagus are challenging due to large surface area of the lining (1-20 cm). Current microendoscopy technologies have shown high specificity; however, its sensitivity is low due to tiny field-of-view (the probe diameter is 100-1000 μm). Therefore, we proposed a novel approach with end-expandable optical fiber brush to collect endoscopic sparse imaging data and deep learning super-resolution enhancement to provide high yield diagnostics.

Conference Presentation

Citation Download Citation

S. Anandasabapathy, X. Zhang, M. Anastasio, R. Richards-Kortum, and E. Petrova "An optical, endoscopic brush for high-yield diagnostics in esophageal cancer", Proc. SPIE 11620, Endoscopic Microscopy XVI, 116200B (8 March 2021); https://doi.org/10.1117/12.2583301

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