A speckle-based method for fast blood flow measurement in deep tissue

Renzhe Bi; Yao Du; Amalina Attia; Jun-Hui Chris Ho; Malini Olivo

doi:10.1117/12.2578106

5 March 2021 A speckle-based method for fast blood flow measurement in deep tissue

Renzhe Bi, Yao Du, Amalina Attia, Jun-Hui Chris Ho, Malini Olivo

Proceedings Volume 11636, Optical Biopsy XIX: Toward Real-Time Spectroscopic Imaging and Diagnosis; 1163606 (2021) https://doi.org/10.1117/12.2578106
Event: SPIE BiOS, 2021, Online Only

Abstract

Blood flow measurement in deep tissue is important because the circulatory system transports oxygen and nutrition to the tissue and removes carbon dioxide out from the tissue. Several non-invasive optical methods were developed for blood flow measurement in deep tissue, such as diffuse correlation spectroscopy (DCS) and diffuse speckle contrast analysis (DSCA). In this paper we will introduce a new speckle-based method for fast blood flow measurement in deep tissue: diffuse speckle pulsatile flowmetry (DSPF). By using a multi-mode fiber for speckle pattern detection, DSPF achieves high blood flow measurement rate of 300 Hz. It has one of the fastest measurement rates of blood flow among non-invasive modalities.

Conference Presentation

Citation Download Citation

Renzhe Bi, Yao Du, Amalina Attia, Jun-Hui Chris Ho, and Malini Olivo "A speckle-based method for fast blood flow measurement in deep tissue", Proc. SPIE 11636, Optical Biopsy XIX: Toward Real-Time Spectroscopic Imaging and Diagnosis, 1163606 (5 March 2021); https://doi.org/10.1117/12.2578106

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