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5 March 2021 Photoacoustic imaging in bone in vitro and in vivo
Jami L. Shepherd, Guillaume Renaud, Pierre Clouzet, Kasper van Wijk
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Proceedings Volume 11642, Photons Plus Ultrasound: Imaging and Sensing 2021; 1164219 (2021) https://doi.org/10.1117/12.2577997
Event: SPIE BiOS, 2021, Online Only
Abstract
Photoacoustic imaging is historically limited to soft-tissues and cannot image the bone interior. However we have recently demonstrated accurate photoacoustic and ultrasonic imaging in a cortical bone model by accounting for both refraction and elastic anisotropy. In this presentation, we will present photoacoustic imaging results in a bone-mimicking replica and ex vivo bovine long bone. We will demonstrate the accuracy of our imaging approach compared to conventional imaging techniques. Further, we will discuss the results of a parametric spectroscopic study of the source laser wavelength and ultrasonic probe to optimise imaging depth and resolution.
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Jami L. Shepherd, Guillaume Renaud, Pierre Clouzet, and Kasper van Wijk "Photoacoustic imaging in bone in vitro and in vivo", Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 1164219 (5 March 2021); https://doi.org/10.1117/12.2577997
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KEYWORDS
Bone
Photoacoustic imaging
Image resolution
Ultrasonography
Photoacoustic spectroscopy
Refraction
Spectroscopy
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