Sparse coding-based denoising and contrast enhancement in low-fluence multi-parametric photoacoustic microscopy

Zhuoying Wang; Yifeng Zhou; Song Hu

doi:10.1117/12.2577980

5 March 2021 Sparse coding-based denoising and contrast enhancement in low-fluence multi-parametric photoacoustic microscopy

Zhuoying Wang, Yifeng Zhou, Song Hu

Author Affiliations +

Proceedings Volume 11642, Photons Plus Ultrasound: Imaging and Sensing 2021; 116421D (2021) https://doi.org/10.1117/12.2577980
Event: SPIE BiOS, 2021, Online Only

Abstract

We report a sparse coding-based two-stage image processing technique for noise reduction and contrast enhancement in photoacoustic microscopy (PAM). We have assessed the performance of this denoising technique using multi-parametric PAM images acquired at different optical fluence levels in vivo. Our results show that this technique can significantly improve the contrast-to-noise ratio (~7 times) and visibility of the microvasculature in low-fluence noisy images, enabling us to reduce the optical fluence by a factor of 5 while maintaining a similar image quality. Moreover, this technique improves the accuracy of quantitative measurements of blood oxygenation and flow in low-fluence PAM images.

Conference Presentation

Citation Download Citation

Zhuoying Wang, Yifeng Zhou, and Song Hu "Sparse coding-based denoising and contrast enhancement in low-fluence multi-parametric photoacoustic microscopy", Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 116421D (5 March 2021); https://doi.org/10.1117/12.2577980

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
PRESENTATION

WATCH
PRESENTATION SAVE TO MY LIBRARY

GET CITATION

KEYWORDS

Denoising

Photoacoustic microscopy

Blood

Image quality

Laser safety

Signal to noise ratio

In vivo imaging

Show All Keywords

Keywords/Phrases

Search In:

Publication Years