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Optical resolution photoacoustic microscopy (OR-PAM), though possessing high lateral resolution, has been limited by its poor axial resolution. In this study, we adapt the delay-multiply-and-sum (DMAS) beamforming technique to improve axial resolution of OR-PAM without physically increasing the detection bandwidth. Experimental OR-PAM A-line signals from a thin absorbing layer were used to verify the efficacy of the proposed frequency domain DMAS method in axial resolution improvement. The improvement achieved with the proposed method was also further verified by imaging microvasculature of mouse ears in vivo.
Sing-Shuo Su,Che-Chou Shen, andMeng-Lin Li
"Improving axial resolution of optical resolution photoacoustic microscopy with frequency domain delay multiply and sum beamforming method", Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 116421E (5 March 2021); https://doi.org/10.1117/12.2582989
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Sing-Shuo Su, Che-Chou Shen, Meng-Lin Li, "Improving axial resolution of optical resolution photoacoustic microscopy with frequency domain delay multiply and sum beamforming method," Proc. SPIE 11642, Photons Plus Ultrasound: Imaging and Sensing 2021, 116421E (5 March 2021); https://doi.org/10.1117/12.2582989