Immunomodulatory property of multispectral near-infrared laser

Wataru Katagiri; Satoshi Kashiwagi

doi:10.1117/12.2577905

5 March 2021 Immunomodulatory property of multispectral near-infrared laser

Wataru Katagiri, Satoshi Kashiwagi

Proceedings Volume 11643, Biophotonics and Immune Responses XVI; 116430N (2021) https://doi.org/10.1117/12.2577905
Event: SPIE BiOS, 2021, Online Only

Abstract

Since biological chromophores typically show several absorption peaks, the specific effects of photobiomodulation would be induced with a combination of two wavelengths, rather than a single wavelength of near-infrared (NIR) light. Single cell live imaging of T cells treated with a combination of 1064 and 1270 nm NIR lasers revealed that the treatment modulated intracellular calcium and reactive oxygen species (ROS) in T cells, which are known to be critical regulators of their function. The treatment with a specific combination of NIR wavelengths of low power laser could be further explored for therapeutic purposes including immunotherapy for cancer and allergy.

Conference Presentation

Citation Download Citation

Wataru Katagiri and Satoshi Kashiwagi "Immunomodulatory property of multispectral near-infrared laser", Proc. SPIE 11643, Biophotonics and Immune Responses XVI, 116430N (5 March 2021); https://doi.org/10.1117/12.2577905

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