The CRISPR platform for diagnostics

Janice Chen

doi:10.1117/12.2589026

5 March 2021 The CRISPR platform for diagnostics

Janice Chen

Proceedings Volume 11662, Frontiers in Biological Detection: From Nanosensors to Systems XIII; 1166206 (2021) https://doi.org/10.1117/12.2589026
Event: SPIE BiOS, 2021, Online Only

Abstract

The programmable nature of sequence-specific targeting by CRISPR-Cas nucleases has revolutionized a wide range of genomic applications and is now emerging as a new method for nucleic acid detection. This talk explores the diversity of CRISPR systems and how their fundamental mechanisms have enabled novel methods for target recognition and readout, highlighting the intersection of biology and engineering. We further discuss the advances and potential for CRISPR-based detection to have an impact across a continuum of diagnostic applications, particularly as it relates to the COVID-19 pandemic.

Conference Presentation

Citation Download Citation

Janice Chen "The CRISPR platform for diagnostics", Proc. SPIE 11662, Frontiers in Biological Detection: From Nanosensors to Systems XIII, 1166206 (5 March 2021); https://doi.org/10.1117/12.2589026

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