Study of properties of virtual laser GB-speckles, generated on nucleotide sequences of the SARS-CoV-2 gene "N"

Sergey Zaytsev; Onega Ulianova; Maria Khizhnyakova; Yuriy Saltykov; Sergey Ulyanov; Alexander Ulyanov; Valentina Feodorova

doi:10.1117/12.2588531

4 May 2021 Study of properties of virtual laser GB-speckles, generated on nucleotide sequences of the SARS-CoV-2 gene "N"

Sergey Zaytsev, Onega Ulianova, Maria Khizhnyakova, Yuriy Saltykov, Sergey Ulyanov, Alexander Ulyanov, Valentina Feodorova

Author Affiliations +

Proceedings Volume 11845, Saratov Fall Meeting 2020: Optical and Nanotechnologies for Biology and Medicine; 118450A (2021) https://doi.org/10.1117/12.2588531
Event: Saratov Fall Meeting 2020, 2020, Saratov, Russian Federation

Abstract

The gene "N" encodes the nucleocapsid structural protein of SARS–CoV-2 virus COVID-19. In the present time, nucleocapsid protein is one of the important targets for the study of both humoral and cellular immune responses to SARS–CoV-2. In this study sequence of the SARS-CoV-2 gene "N", which is encoding the relevant structural protein, has been transformed into the sequence of numbers with purpose to generate gene-based speckles. Differences in the initial nucleotide sequences have been found and characterized by means of virtual laser gene-based speckles (GBspeckles). It has been shown, that at the interference of two SARS–CoV-2 GB-speckle-patterns, two types of interference pictures are forming: quasi-random speckle structure without interference fringes or fringes, modulated by speckles. It has been demonstrated that implication of interference of two GB-speckles, generated on the virus nucleotide sequences, can be considered as a new direction in modern bioinformatics.

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Sergey Zaytsev, Onega Ulianova, Maria Khizhnyakova, Yuriy Saltykov, Sergey Ulyanov, Alexander Ulyanov, and Valentina Feodorova "Study of properties of virtual laser GB-speckles, generated on nucleotide sequences of the SARS-CoV-2 gene "N"", Proc. SPIE 11845, Saratov Fall Meeting 2020: Optical and Nanotechnologies for Biology and Medicine, 118450A (4 May 2021); https://doi.org/10.1117/12.2588531

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