Longitudinal in-vivo quantification of tumour microvasculature heterogeneity via optical coherence tomography (OCT) angiography in a pre-clinical model of radiation therapy

Nader Allam; W. Jeffrey Zabel; Blake Jones; Valentin Demidov; Edward Taylor; I. Alex Vitkin

doi:10.1117/12.2616024

9 December 2021 Longitudinal in-vivo quantification of tumour microvasculature heterogeneity via optical coherence tomography (OCT) angiography in a pre-clinical model of radiation therapy

Nader Allam, W. Jeffrey Zabel, Blake Jones, Valentin Demidov, Edward Taylor, I. Alex Vitkin

Author Affiliations +

Proceedings Volume 11924, Optical Coherence Imaging Techniques and Imaging in Scattering Media IV; 119240G (2021) https://doi.org/10.1117/12.2616024
Event: European Conferences on Biomedical Optics, 2021, Online Only

Abstract

Stereotactic body radiotherapy’s radiobiological mechanism of action is unknown, impeding development of adaptive irradiation schedules. A new vascular biomarker with predictive potential of tumour radiation response and hypoxia is extracted via OCT angiography longitudinally.

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Nader Allam, W. Jeffrey Zabel, Blake Jones, Valentin Demidov, Edward Taylor, and I. Alex Vitkin "Longitudinal in-vivo quantification of tumour microvasculature heterogeneity via optical coherence tomography (OCT) angiography in a pre-clinical model of radiation therapy", Proc. SPIE 11924, Optical Coherence Imaging Techniques and Imaging in Scattering Media IV, 119240G (9 December 2021); https://doi.org/10.1117/12.2616024

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