Phononic endo-microscopy in 3D

Salvatore La Cavera III; Fernando Perez-Cota; Richard J. Smith; Matt Clark

doi:10.1117/12.2609611

3 March 2022 Phononic endo-microscopy in 3D

Salvatore La Cavera III, Fernando Perez-Cota, Richard J. Smith, Matt Clark

Proceedings Volume 11937, Endoscopic Microscopy XVII; 1193708 (2022) https://doi.org/10.1117/12.2609611
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Optical fibres have revolutionised clinical practice in the form of the optical endoscope, and are now providing the framework for an entirely new endoscopic paradigm: all-optical ultrasound. Ultrasonic techniques, and in particular those based on the opto-acoustic effect of Brillouin scattering, present a number of advantages compared to purely optical techniques. High contrast imaging can be achieved without the use of fluorescent labels, elastic properties of the specimen can be quantified, lateral resolution is provided by optics, and axial resolution is provided by sub-optical wavelength non-destructive phonons. Here we present an optical fibre-based time resolved Brillouin scattering system, called a phonon probe, which is capable of measuring nanometric topography and elastic properties in parallel from microscopic samples. We also demonstrate that our technique is inherently compatible with standard coherent imaging bundles, which will drive the technology towards future in vivo applications.

Conference Presentation

Citation Download Citation

Salvatore La Cavera III, Fernando Perez-Cota, Richard J. Smith, and Matt Clark "Phononic endo-microscopy in 3D", Proc. SPIE 11937, Endoscopic Microscopy XVII, 1193708 (3 March 2022); https://doi.org/10.1117/12.2609611

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