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A novel wearable MRg-NIRST system for breast cancer detection has been designed and developed. In this prototype, eight (8) flex circuit strips, each with six (6) photo-detectors (PDs) and six (6) source fibers, are attached to the breast to collect diffused light. A 6x48 fiber switch and 48 side-firing fibers deliver intensity modulated laser light at six (6) near-infrared wavelengths. Light intensity at each of 2304 source-detector positionsis obtained for T2-MRI guided 3D NIRST image reconstruction. In phantom testing, reconstructed images showed the contrast between tumor/inclusion and normal/background.
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Mengyang Zhao, Xu Cao, Mingwei Zhou, Jinchao Feng, Luxi Xia, Brian W. Pogue, Keith D. Paulsen, Shudong Jiang, "MRI-guided near-infrared spectroscopic tomography (MRg-NIRST): system development for wearable, simultaneous NIRS and MRI imaging," Proc. SPIE 11952, Multimodal Biomedical Imaging XVII, 119520E (2 March 2022); https://doi.org/10.1117/12.2607983