Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation

Daniel J. McAuliffe Sr.; Steven L. Jacques; Amy S. Hayes

doi:10.1117/12.17615

1 June 1990 Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation

Daniel J. McAuliffe Sr., Steven L. Jacques, Amy S. Hayes

Proceedings Volume 1202, Laser-Tissue Interaction; (1990) https://doi.org/10.1117/12.17615
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

A striking consequence of 248-nm excimer laser irradiation of skin is a stable vivid blue fluorescence easily visualized under UVA illumination. Its spectral properties (excitation maximum at "335 nm; emission maximum at ''43O nm) are somewhat similar to those of the fluorescent pigments associated with aging of tissue and peroxidation of lipids, and the fluorescent pigments formed during exposure to high temperatures. This study explores the spectral properties, magnitude, dose response, and laser pulse intensity dependence of this phenomenon in both isolated stratum corneum and epidermal cell suspensions from human skin.

Citation Download Citation

Daniel J. McAuliffe Sr., Steven L. Jacques, and Amy S. Hayes "Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation", Proc. SPIE 1202, Laser-Tissue Interaction, (1 June 1990); https://doi.org/10.1117/12.17615

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available