Paper
29 April 2022 Stimulation of heart pacemakers cells using pulsed infrared radiation
M. A. Ansari, H. Tajarenejad, S. Akbari, M. Zakeri, S. M. Hamidi
Author Affiliations +
Proceedings Volume 12192, Optical Technologies for Biology and Medicine; 1219205 (2022) https://doi.org/10.1117/12.2623909
Event: XXV Annual Conference Saratov Fall Meeting 2021; and IX Symposium on Optics and Biophotonics, 2021, Saratov, Russian Federation
Abstract
Optical pacing (OP) has been proved to be a feasible noninvasive alternative to electrical pacing in recent years. IR lasers can be utilized for this purpose because of the absorption rate of infrared light, particularly wavelengths of 1450 nm, in biological tissue. As a result, the goal of this research is to look at the thermal effects of infrared radiation on cardiac pacemaker cells. To begin, we investigate the heat generation and temperature increases caused by IR pulses in biological tissues as a function of pulse length and radiant exposure depth. The toad heart is then treated with a pulsed infrared laser in an experiment (wavelength of 1450 nm). By measuring the toad's heart rhythm, the temperature effect of IR radiation on its cardiac pacemaker cells is examined. The findings reveal that the thermal effect of IR pulses can alter cardiac pacemaker cells based on variations in the T wave amplitude in the toad heart rhythm. In conclusion, this work shows that non-invasive IR pulses may successfully stimulate cardiac pacemaker cells.
© (2022) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
M. A. Ansari, H. Tajarenejad, S. Akbari, M. Zakeri, and S. M. Hamidi "Stimulation of heart pacemakers cells using pulsed infrared radiation", Proc. SPIE 12192, Optical Technologies for Biology and Medicine, 1219205 (29 April 2022); https://doi.org/10.1117/12.2623909
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KEYWORDS
Heart

Infrared radiation

Radiation effects

Temperature metrology

Photothermal effect

Calcium

Infrared lasers

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