Differentiation of lumpy skin disease virus and sheeppox virus strains using of GB-speckles, generated for the nucleotide sequences of the gene GPCR

Yury Saltykov; Anna Kolosova; Sergey Ulyanov; Onega Ulianova; Alexander Ulyanov; Valentina Feodorova

doi:10.1117/12.2626280

29 April 2022 Differentiation of lumpy skin disease virus and sheeppox virus strains using of GB-speckles, generated for the nucleotide sequences of the gene GPCR

Yury Saltykov, Anna Kolosova, Sergey Ulyanov, Onega Ulianova, Alexander Ulyanov, Valentina Feodorova

Author Affiliations +

Proceedings Volume 12192, Optical Technologies for Biology and Medicine; 121920L (2022) https://doi.org/10.1117/12.2626280
Event: XXV Annual Conference Saratov Fall Meeting 2021; and IX Symposium on Optics and Biophotonics, 2021, Saratov, Russian Federation

Abstract

The nucleotide sequences of the GPCR gene of Lumpy Skin Disease Virus (LSDV) and Sheeppox Virus (SPPV) strains have been transformed into 2D realizations of GB-speckles (Gene-Based speckles). Based on the analysis of statistical properties of corresponding GB-speckles, a possibility of differentiation between wild field LSDV and the SPPV strains which could be used as heterologous vaccines against Lumpy Skin Disease has been shown. It has been demonstrated that an application of the GB-speckles has the great perspectives from viewpoint of modern bioinformatics.

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Yury Saltykov, Anna Kolosova, Sergey Ulyanov, Onega Ulianova, Alexander Ulyanov, and Valentina Feodorova "Differentiation of lumpy skin disease virus and sheeppox virus strains using of GB-speckles, generated for the nucleotide sequences of the gene GPCR", Proc. SPIE 12192, Optical Technologies for Biology and Medicine, 121920L (29 April 2022); https://doi.org/10.1117/12.2626280

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