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A novel MRI-guided near-infrared spectroscopic tomographic imaging system (NIRST) has been developed for breast cancer detection. NIRST imaging for an entire breast can be simultaneously carried out during MRI scanning in less than 4 minutes. Reconstructed phantom images showed clear contrast of a 20 mm inclusion to the background, and the total hemoglobin (HbT) and water concentration values estimated from the reconstructed images of a normal subject were in the same range as those obtained in our previous imaging studies.
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Mengyang Zhao, Xu Cao, Mingwei Zhou, Jinchao Feng, Luxi Xia, Brian Pogue, Keith Paulsen, Shudong Jiang, "MRI-guided near-infrared spectroscopic tomographic system for breast cancer imaging: phantom and normal-subject studies," Proc. SPIE 12371, Multimodal Biomedical Imaging XVIII, 1237104 (6 March 2023); https://doi.org/10.1117/12.2647571