Numerical simulation of thermal damage in atherosclerotic plaque using microwave

Yong Liu; Ji-wen Hu; Ya-qian Xie

doi:10.1117/12.2673574

4 April 2023 Numerical simulation of thermal damage in atherosclerotic plaque using microwave

Yong Liu, Ji-wen Hu, Ya-qian Xie

Proceedings Volume 12603, Biophysical Society of GuangDong Province Academic Forum: Precise Photons and Life Health (PPLH 2022); 126030B (2023) https://doi.org/10.1117/12.2673574
Event: 2022 Biophysical Society of Guang Dong Province Academic Forum - Precise Photons and Life Health (PPLH 2022), 2022, Guangzhou, China

Abstract

The purpose of this study is to explore the thermal damage of microwave to atherosclerotic plaques in order to achieve the purpose of treating atherosclerosis. In this paper, a fluid-solid-heat coupling model of thermal ablation of atherosclerotic plaque is established (The coupling model of blood-plaque-electromagnetic wave is studied in this paper, in which the thermal ablation of atherosclerotic plaque means that the electromagnetic wave is used to generate heat, and the temperature of atherosclerotic plaque tissue rises. If the cells in it reach the threshold of death temperature, they will be killed, so as to achieve the purpose of thermal ablation.). The electromagnetic field and bio-thermal equation are solved and analyzed by finite element method. By calculating the temperature and thermal damage distribution of microwave on atherosclerotic plaque, the effect of microwave on thermal ablation of atherosclerotic plaque was evaluated. The results show that the thermal damage degree of atherosclerotic plaque is positively correlated with electromagnetic wave frequency, electromagnetic wave power and heating time. The model shows that electromagnetic wave hyperthermia may provide a new therapeutic mode for thermal ablation of atherosclerotic plaques.

Citation Download Citation

Yong Liu, Ji-wen Hu, and Ya-qian Xie "Numerical simulation of thermal damage in atherosclerotic plaque using microwave", Proc. SPIE 12603, Biophysical Society of GuangDong Province Academic Forum: Precise Photons and Life Health (PPLH 2022), 126030B (4 April 2023); https://doi.org/10.1117/12.2673574

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available