In vivo monitoring of hemoglobin derivative concentrations and saturations in rat burn wounds using a red-green-blue camera

Md Anowar Parvez; Kaisei Okura; Kazuhiro Yashiro; Yasuyuki Tsunoi; Daizoh Saitoh; Shunichi Sato; Izumi Nishidate

doi:10.1117/12.3007929

20 September 2023 In vivo monitoring of hemoglobin derivative concentrations and saturations in rat burn wounds using a red-green-blue camera

Md Anowar Parvez, Kaisei Okura, Kazuhiro Yashiro, Yasuyuki Tsunoi, Daizoh Saitoh, Shunichi Sato, Izumi Nishidate

Author Affiliations +

Proceedings Volume 12608, Biomedical Imaging and Sensing Conference; 1260815 (2023) https://doi.org/10.1117/12.3007929
Event: Optics and Photonics International Congress, 2023, Yokohama, Japan

Abstract

Assessments of the burn depth is very important for shorter healing time, fewer infection, better functional and aesthetic result and reduce hospital stay. We investigated a red-green-blue camera-based diffuse reflectance imaging for monitoring of oxygenated hemoglobin (HbO), deoxygenated hemoglobin (HbR), methemoglobin (metHb), tissue oxygen saturation (StO₂) and methemoglobin saturation (StMet) in superficial dermal burn (SDB), deep dermal burn (DDB) and non-burned skin in rats. The canonical discriminant analysis with the concentrations and saturations of hemoglobin derivatives showed good separation between SDB, DDB, and non-burned skin.

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Md Anowar Parvez, Kaisei Okura, Kazuhiro Yashiro, Yasuyuki Tsunoi, Daizoh Saitoh, Shunichi Sato, and Izumi Nishidate "In vivo monitoring of hemoglobin derivative concentrations and saturations in rat burn wounds using a red-green-blue camera", Proc. SPIE 12608, Biomedical Imaging and Sensing Conference, 1260815 (20 September 2023); https://doi.org/10.1117/12.3007929

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