Laser speckle correlation microscopy system to image microvascular perfusion

Soumyajit Sarkar; Mohammad Zaffar; Hari M. Varma

doi:10.1117/12.2670792

9 August 2023 Laser speckle correlation microscopy system to image microvascular perfusion

Soumyajit Sarkar, Mohammad Zaffar, Hari M. Varma

Proceedings Volume 12628, Diffuse Optical Spectroscopy and Imaging IX; 1262827 (2023) https://doi.org/10.1117/12.2670792
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

Laser speckle contrast imaging (LSCI) methods are extensively used in assessment of blood flow to detect various pathological conditions in different parts of human body. In contrast to LSCI being deployed for larger region of interest (few centimeters), we present a laser speckle imaging at microscopic level. Rather than utilizing the conventional speckle contrast, we use intensity auto-correlation using recently developed Multi-step Volterra Integral method(MVIM) to quantify the micro-perfusion. The proposed laser speckle correlation microscopy (LSCM) system is validated using microfluidic flow phantom experiments.

(2023) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Soumyajit Sarkar, Mohammad Zaffar, and Hari M. Varma "Laser speckle correlation microscopy system to image microvascular perfusion", Proc. SPIE 12628, Diffuse Optical Spectroscopy and Imaging IX, 1262827 (9 August 2023); https://doi.org/10.1117/12.2670792

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