Plano-concave optical sensor for transcranial photoacoustic measurements

Thomas Kirchner; Claus Villringer; Marko Gutke; Jan Laufer

doi:10.1117/12.2675593

11 August 2023 Plano-concave optical sensor for transcranial photoacoustic measurements

Thomas Kirchner, Claus Villringer, Marko Gutke, Jan Laufer

Proceedings Volume 12631, Opto-Acoustic Methods and Applications in Biophotonics VI; 126310R (2023) https://doi.org/10.1117/12.2675593
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

Biomedical photoacoustics is usually used to image absorption-based contrast in soft tissues up to depths of several centimeters and with sub-millimeter resolution. By contrast, measuring Photoacoustic (PA) signals through hard bone tissue shows severe signal degradation due to aberration and high attenuation of high frequency acoustic signal components. This is particularly noticeable when measuring through thicker, human, skull bone. Which is the main reason why transcranial PA imaging in humans has so far proved challenging to implement. To tackle this challenge, we developed an optical resonator sensor based on a previous planar-concave design. This sensor was found to be highly suitable for measuring the low-pressure amplitude and low acoustic frequency signals that are transmitted through human cranial bone. A plano-concave optical resonator sensor was fabricated to provide high sensitivity in the acoustic frequency range of DC to around 2 MHz, a low noise equivalent pressure and a small active element size enabling it to significantly outperform conventional piezoelectric transducers when measuring PA waves transmitted through ex vivo human cranial bones.

(2023) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Thomas Kirchner, Claus Villringer, Marko Gutke, and Jan Laufer "Plano-concave optical sensor for transcranial photoacoustic measurements", Proc. SPIE 12631, Opto-Acoustic Methods and Applications in Biophotonics VI, 126310R (11 August 2023); https://doi.org/10.1117/12.2675593

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