Simulating optical memory effects and the scanning of foci using wavefront shaping in tissue-like scattering media

Jake A. J. Bewick; Peter R. T. Munro; Simon R. Arridge; James A. Guggenheim

doi:10.1117/12.2670438

11 August 2023 Simulating optical memory effects and the scanning of foci using wavefront shaping in tissue-like scattering media

Jake A. J. Bewick, Peter R. T. Munro, Simon R. Arridge, James A. Guggenheim

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Proceedings Volume 12632, Optical Coherence Imaging Techniques and Imaging in Scattering Media V; 126321H (2023) https://doi.org/10.1117/12.2670438
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

Wavefront shaping could enable focusing light deep inside scattering media, increasing the depth and resolution of imaging techniques like optical microscopy and optical coherence tomography. However, factors like rapid decorrelation times due to microscale motion and thermal variation make focusing on living tissue difficult. A way to ease the requirements could be exploiting prior information provided by memory effects. For example, this might allow partially or wholly scanning a focus. To study this and related ideas, a computational model was developed to simulate the generation and correlations of foci formed by WFS in scattering media. Predictions of the angular memory range were consistent with experimental observations. Furthermore, correlations observed between optical phase maps required to focus on different positions suggested correlation-based priors might enable accelerated focusing. This work could pave the way to faster optical focusing and thus deeper imaging in living tissue.

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Jake A. J. Bewick, Peter R. T. Munro, Simon R. Arridge, and James A. Guggenheim "Simulating optical memory effects and the scanning of foci using wavefront shaping in tissue-like scattering media", Proc. SPIE 12632, Optical Coherence Imaging Techniques and Imaging in Scattering Media V, 126321H (11 August 2023); https://doi.org/10.1117/12.2670438

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KEYWORDS

Scattering media

Tissues

Light scattering

Wavefronts

Geometrical optics

Speckle pattern

Incident light

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