Influential factors of stroke: depression, Alzheimer's disease

Chao Ping

doi:10.1117/12.2691854

7 September 2023 Influential factors of stroke: depression, Alzheimer's disease

Chao Ping

Proceedings Volume 12789, International Conference on Modern Medicine and Global Health (ICMMGH 2023); 127892O (2023) https://doi.org/10.1117/12.2691854
Event: International Conference on Modern Medicine and Global Health (ICMMGH 2023), 2023, Oxford, United Kingdom

Abstract

The research on risk factors and influencing factors of stroke is a hot field of current research. Important progress has been made in the study of stroke-related risk factors such as hypertension, diabetes, atrial fibrillation, diet, physical activity, smoking, and alcohol abuse. However, there are still gaps in the study of immutable risk factors such as age, sex, race, transient ischemic attack (TIA), and psychological factors that are important triggers of stroke. In addition, it has been demonstrated that stroke poses a danger for developing Alzheimer's disease, but there is still a lack of uniform explanation as to whether Alzheimer's disease is a risk factor for stroke. Therefore, combining previous research and relevant literature, this article mainly analyzes two parts: The first part analyzes the causes of the high incidence of stroke in the elderly from a psychological perspective, mainly analyzing the impact of depression, and the second part explores whether Alzheimer's disease poses a danger for developing stroke by analyzing the potential common pathway between Alzheimer's disease and stroke. The elderly is more likely to have negative emotions such as depression, which can directly induce stroke, or indirectly increase the risk of stroke by increasing the risk of hypertension, diabetes, etc. The susceptibility to negative emotions is one of the psychological factors that contributes to the high incidence of stroke in the elderly. Alzheimer's disease can induce or exacerbate stroke. The dementia and cognitive impairment brought on by Alzheimer's disease can raise the chance of stroke. There are potential mechanism connections between the two on amyloid proteins β (Aβ) toxicity, Tau protein, and oxidative stress.

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Chao Ping "Influential factors of stroke: depression, Alzheimer's disease", Proc. SPIE 12789, International Conference on Modern Medicine and Global Health (ICMMGH 2023), 127892O (7 September 2023); https://doi.org/10.1117/12.2691854

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KEYWORDS

Alzheimer disease

Proteins

Dementia

Emotion

Mental disorders

Cardiovascular disorders

Atrial fibrillation

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