Towards high-accuracy noninvasive ocular melanoma imaging and prognostics

Vsevolod Cheburkanov; Vladislav Yakovlev

doi:10.1117/12.3003468

12 March 2024 Towards high-accuracy noninvasive ocular melanoma imaging and prognostics

Vsevolod Cheburkanov, Vladislav Yakovlev

Proceedings Volume 12836, Optical Biopsy XXII: Toward Real-Time Spectroscopic Imaging and Diagnosis; 128360F (2024) https://doi.org/10.1117/12.3003468
Event: SPIE BiOS, 2024, San Francisco, California, United States

Conference Poster

Abstract

Ocular melanoma, albeit being rare, is an aggressive type of cancer, developing within the interior of a person’s eye. Location of this malignant growth increases severity of this type of cancer. It commonly develops in the middle layer of the eye, referred to as uvea. Melanoma develops from melanocytes, with a 90% of cases observed in posterior uvea (choroid). Complications from this type of cancer include metastasis in the liver. To avoid such outcome and improve treatments we are proposing application of fluorescence lifetime imaging microscopy (FLIM) to distinguish metastatic and non-metastatic melanomas. In the reported here preliminary study, we evaluate the system requirements for FLIM imaging of melanin-based tissues and structures.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Vsevolod Cheburkanov and Vladislav Yakovlev "Towards high-accuracy noninvasive ocular melanoma imaging and prognostics", Proc. SPIE 12836, Optical Biopsy XXII: Toward Real-Time Spectroscopic Imaging and Diagnosis, 128360F (12 March 2024); https://doi.org/10.1117/12.3003468

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