The development of ionizing radiation acoustic imaging (iRAI) for mapping the dose deep in the patient body during radiation therapy

Wei Zhang; Dale Litzenberg; Yaocai Huang; Kai-Wei Chang; Ibrahim Oraiqat; Scott Hadley; Eduardo G. Moros; Man Zhang; Paul L. Carson; Kyle C. Cuneo; Issam EI Naqa; Xueding Wang

doi:10.1117/12.3000346

12 March 2024 The development of ionizing radiation acoustic imaging (iRAI) for mapping the dose deep in the patient body during radiation therapy

Wei Zhang, Dale Litzenberg, Yaocai Huang, Kai-Wei Chang, Ibrahim Oraiqat, Scott Hadley, Eduardo G. Moros, Man Zhang, Paul L. Carson, Kyle C. Cuneo, Issam EI Naqa, Xueding Wang

Author Affiliations +

Proceedings Volume 12842, Photons Plus Ultrasound: Imaging and Sensing 2024; 1284207 (2024) https://doi.org/10.1117/12.3000346
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Ionizing radiation acoustic imaging (iRAI) provides the potential to map the radiation dose during radiotherapy in real time. Described here is the development of iRAI volumetric imaging system in mapping the three-dimensional (3D) radiation dose deposition of clinical radiotherapy treatment plan with patient receiving radiation to liver tumor. The real-time visualizations of radiation dose delivered have been archived in patients with liver tumor under a clinical linear accelerator. This proof-of-concept study demonstrated the potential of iRAI to map the dose distribution in deep body during radiotherapy, potentially leading to personalized radiotherapy with optimal efficacy and safety.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Wei Zhang, Dale Litzenberg, Yaocai Huang, Kai-Wei Chang, Ibrahim Oraiqat, Scott Hadley, Eduardo G. Moros, Man Zhang, Paul L. Carson, Kyle C. Cuneo, Issam EI Naqa, and Xueding Wang "The development of ionizing radiation acoustic imaging (iRAI) for mapping the dose deep in the patient body during radiation therapy", Proc. SPIE 12842, Photons Plus Ultrasound: Imaging and Sensing 2024, 1284207 (12 March 2024); https://doi.org/10.1117/12.3000346

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