Analysis and evaluation of measurement errors in Mueller matrix microscopy

Tongyu Huang; Zheng Hu; Hui Ma

doi:10.1117/12.3001510

12 March 2024 Analysis and evaluation of measurement errors in Mueller matrix microscopy

Tongyu Huang, Zheng Hu, Hui Ma

Proceedings Volume 12845, Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2024; 1284503 (2024) https://doi.org/10.1117/12.3001510
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Mueller matrix microscopy can provide a comprehensive description of sample’s polarization properties non-invasively, and has shown attractive applications in many different fields such as biomedicine, marine particle monitoring, and material identification. Mueller matrix measurements are based on multiple light intensity measurements under illuminations of different polarization states, therefore have more error sources compared to other imaging methods, which reduce the image quality and hinder efforts for quantitatively characterizing the polarization features of weak polarization biological samples such as living cells. Measurement errors of a Mueller matrix microscope are mainly classified into three categories including systematical error, random noise, and mismatch error. In this paper, based on the physical realizability of Mueller matrix and image frequency analysis, different categories and sources of measurement errors in Mueller matrix microscopy are analyzed in detail, a no-reference Mueller matrix image quality evaluator (MIQE) is also proposed to estimate the error level of biomedical sample’s Mueller matrix.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Tongyu Huang, Zheng Hu, and Hui Ma "Analysis and evaluation of measurement errors in Mueller matrix microscopy", Proc. SPIE 12845, Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2024, 1284503 (12 March 2024); https://doi.org/10.1117/12.3001510

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