Radiomics, a burgeoning field within medical imaging, has gained momentum for its potential to provide nuanced insights into lesion characteristics. This study introduces a pioneering approach to benchmarking radiomic features, delving into their correlations with ground truth measurements and subsequent clustering patterns. By analyzing 59 simulated lesions mined from the publicly available QIDW Liver II Hybrid Dataset, a vast array of radiomic features were extracted and evaluated using Pyradiomics. A total of 2060 features are correlated with ground truth volume and contrast measurements, revealing intricate relationships. Novel co-clustering patterns emerge, underscoring the versatility and complexity of radiomic features. These findings not only contribute to lesion characterization precision but also advanced our understanding of radiomic intricacies. The presented research holds potential to refine radiomics-driven medical insights, paving the way for more informed clinical decision-making and improved patient care.
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